Description
This synthetic cyclic lactam analog of α-MSH provides a non-selective melanocortin receptor agonist tool for studying the MC1R–MC5R receptor family. Its broad receptor engagement profile enables investigation of diverse melanocortin-mediated physiological pathways. For research use only.
- Melanogenesis & MC1R Signaling: Investigated for cAMP-PKA-MITF pathway activation in melanocyte models, driving tyrosinase expression and eumelanin synthesis kinetics.
- MC4R-Mediated Appetite Regulation: Studied for hypothalamic melanocortin-4 receptor agonism and its downstream effects on POMC neuron activation and feeding behavior circuits.
- Erectile & Sexual Function Pathways: Explored for central MC3R/MC4R-mediated activation of paraventricular nucleus oxytocinergic neurons in autonomic arousal research models.









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